{"id":101,"date":"2017-07-22T15:47:05","date_gmt":"2017-07-22T19:47:05","guid":{"rendered":"https:\/\/eportfolios.macaulay.cuny.edu\/odonnell17online\/?page_id=101"},"modified":"2025-06-09T20:45:32","modified_gmt":"2025-06-09T20:45:32","slug":"week-12-drug-discovery-development","status":"publish","type":"page","link":"https:\/\/openlab.macaulay.cuny.edu\/sf-aug-4\/week-12-drug-discovery-development\/","title":{"rendered":"Unit 12: Drug Discovery &amp; Development"},"content":{"rendered":"<h3>Summary:<\/h3>\n<p>This week we keep moving down in scale to the level of cells and molecules. There will be a lot of medical discussions in the next few weeks, which I know is an interest of many in our class. Unit 12 is about Drug Discovery and Development with specific examples from clinical trials having to do with cancer. We&#8217;ll be bringing in some Structural Biology when we talk about creating drugs and then we&#8217;ll take an in depth look into how drugs come to market. In the process, we&#8217;ll be talking a lot about experimental design and models.<\/p>\n<h3>Learning Objectives:<\/h3>\n<ul>\n<li>understand the importance of models to the chemistry and biology involved in drug development<\/li>\n<li>explore experimental design in clinical drug trials<\/li>\n<\/ul>\n<h3>Unit 12, Class 22 [day\/date] Required Readings\/Videos:<\/h3>\n<ol>\n<li><strong>SF video:<\/strong> <a href=\"https:\/\/youtu.be\/Gu0knOtpAE8\">Drug Discovery and Development.<\/a><\/li>\n<li><strong>Reading: <\/strong><a href=\"https:\/\/openstax.org\/books\/biology\/pages\/3-introduction\">Chapter 3<\/a>: Biological Macromolecules <em>from\u00a0<\/em> Biology. 21 October 2016.<\/li>\n<li><strong>Reading:<\/strong>\u00a0Gorson and Holford 2016. Small Packages, Big Returns: Uncovering the Venom Diversity of Small Invertebrate Conoidean Snails.\u00a0<i>Integrative and Comparative Biology. <\/i>56(5):962-972.<\/li>\n<\/ol>\n<p>Unit 12, Class 22 [day\/date] OPTIONAL Reading:<\/p>\n<p>Rogers. 2022. <a href=\"https:\/\/www.scientificamerican.com\/article\/venomous-snail-unlocks-new-diabetes-drugs\/\">Venomous Snail Unlocks New Diabetes Drugs.<\/a> <em>Scientific American.<\/em><\/p>\n<h3>Unit 12, Class 22 [day\/date] Self-Assessment<\/h3>\n<p>[insert form]<\/p>\n<h3>Unit 12, Class 23 [day\/date] Required Readings\/Videos<\/h3>\n<ol>\n<li><strong>Video: <\/strong><a href=\"https:\/\/www.ted.com\/talks\/francis_collins_we_need_better_drugs_now?subtitle=en\">TED talk: Collins \u2013 We need better drugs now<\/a>.<\/li>\n<li><strong>Reading: <\/strong>Mullard. 2012. Drug repurposing progammes get lift off. <em>Nature<\/em>. 11:1-2.<\/li>\n<\/ol>\n<h3>Unit 12, Class 23 [day\/date]Self-Assessment<\/h3>\n<p>[insert form]<\/p>\n<h3>Unit 12 Major Assignments<\/h3>\n<p>Poster first draft is due [time\/date]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Summary: This week we keep moving down in scale to the level of cells and molecules. There will be a lot of medical discussions in the next few weeks, which I know is an interest of many in our class. Unit 12 is about Drug Discovery and Development with specific examples from clinical trials having [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"portfolio_post_id":0,"portfolio_citation":"","portfolio_annotation":"","openlab_post_visibility":"","footnotes":""},"class_list":["post-101","page","type-page","status-publish","hentry","post-preview"],"_links":{"self":[{"href":"https:\/\/openlab.macaulay.cuny.edu\/sf-aug-4\/wp-json\/wp\/v2\/pages\/101","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/openlab.macaulay.cuny.edu\/sf-aug-4\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/openlab.macaulay.cuny.edu\/sf-aug-4\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/openlab.macaulay.cuny.edu\/sf-aug-4\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/openlab.macaulay.cuny.edu\/sf-aug-4\/wp-json\/wp\/v2\/comments?post=101"}],"version-history":[{"count":1,"href":"https:\/\/openlab.macaulay.cuny.edu\/sf-aug-4\/wp-json\/wp\/v2\/pages\/101\/revisions"}],"predecessor-version":[{"id":6685,"href":"https:\/\/openlab.macaulay.cuny.edu\/sf-aug-4\/wp-json\/wp\/v2\/pages\/101\/revisions\/6685"}],"wp:attachment":[{"href":"https:\/\/openlab.macaulay.cuny.edu\/sf-aug-4\/wp-json\/wp\/v2\/media?parent=101"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}